In the beginning of this year, a research paper was...

In the beginning of this year, a research paper was published in The Journal of the American Medical Association. This paper discussed a clinical trial of which they used vitamin E and Memantine as a way to reduce the effects of AD. This trial started in 2007, but before that, there were trials studying the effects of antioxidants in AD patients. Both trials hypothesized that the use of antioxidants and another variable could reduce the effects of AD. One trial, studying the effects of antioxidants on cerebrospinal fluid (CSF) biomarkers, which are commonly found in patients with AD, was a double blind study, which took place between 2006 and 2008. This study used three different variables of drugs were given to the patients in a 16-week†¦show more content†¦Also lowering the CSF F2-isoprostane levels in the E/C/ALA group reduced the oxidative stress in the brain. However, this raised the patient’s cognitive decline, which would is the opposite of what the next trail wanted to do. The next trail thought that the use of antioxidants would reduce the progression of mild to moderate AD. This trial began in August of 2007 and ended in September of 2012. The participants were given 1 of 4 drugs: alpha tocopherol (vitamin E), memantine, the combination, or a placebo. Alpha tocopherol, or vitamin E, is a fat-soluble vitamin and antioxidant. It has been studied in patients with moderately sever AD and mild cognitive impairment (MCI). In the patients with moderately sever AD, it was found that vitamin E was effective in the dose of 2000 ID/d, however it was not effective in patients with MCI. Memantine, a N-methyl-D-aspartate (NMDA) antagonist, was used in 2 randomized clinical trials before and both featured AD patients. Each of these studies however were only 6 months, meaning there was not enough time to study the long term effects of using this drug. The participants chosen for this study were veterans who were diagnosed with possible or probable mil d to moderately sever AD. These patients had a MMSE between 12 and 26, where the other trial used patientsShow MoreRelatedThe Cost Of Post Secondary School Education1176 Words   |  5 Pagesshortfalls and wrong use of cost offsetting. A recent article published in the Wall Street Journal indicates that students across America are plunging into more debt due to loans taken to pay their college education. Considering that America has experienced severe shortages of employees in the science related courses, rising costs of higher education continue to create more concern. 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